Proteinuric Potentials of Angiotensin II, (des-Asp1)-Angiotensin II, and (des-Asp1, des-Arg2)-Angiotensin II in Rats.
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چکیده
منابع مشابه
Characterization of immunoreactive angiotensin in canine cerebrospinal fluid as Des-Asp1-angiotensin II.
1. Immunoreactive angiotensin II was measured in cerebrospinal fluid of four normal dogs. 2. The migration of this immunoreactive angiotensin II on polyacrylamide-slab gel electrophoresis was identical with the migration of the heptapeptide, Des-Asp1-angiotensin II, in each case. 3. The biological activity of the material from canine cerebrospinal fluid in a pressor bioassay was similar to that...
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Johannsen UJ: Phentolamine and isoproterenol: Comparison of effects on vascular resistance and oxygen uptake in skeletal muscle during hypotension. J Pharmacol Exp Ther 199: 353359, 1976 Zelis R, Mason DT, Braunwald E: A comparison of the effects of vasodilator stimuli on peripheral resistance vessels in normal subjects and in patients with congestive heart failure. J Clin Invest 47: 960-970, 1...
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Objective: Angiotensin II (Ang II), the main product of renin-angiotensin system (RAS) has a well-known role in cardiovascular regulation. Over-production of Ang II is one of the important underlying mechanisms of hypertension. In this study, the effect of crocin on cardiovascular responses in rats with acute hypertension induced by Ang II was evaluated. Materials and methods: Rats were divided...
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The substrate specificity of tonin from rat submaxillary gland was examined with a series of synthetic peptides encompassing the C-terminus of the decapeptide substrate angiotensin I. In contrast to angiotensin I-converting enzyme from plasma or lung, only angiotensin I, (des-Asp1)-angiotensin I, and (des-Asp1, des-Arg2)-angiotensin I are substrates of tonin with Km values of 34.5 muM, 39.3 muM...
متن کاملRole of converting enzyme in the responses of rabbit atria, aortas, and adrenal zona glomerulosa to [des-Asp1]angiotensin I.
1. Donahoe PK, Osmond JD, Stewart DR, Hendren WH: Renal parenchytnal tolerance to artery occlusion. Ann Surg 178: 138-142, 1973 2. Balint P, Fekete A, Munkacsi I: Renal function following complete ligation of the renal artery. Experientia 21: 714-715, 1965 3. Fekete A: Functions of the kidney after ligation of the renal artery. Acta Med Acad Sci Hung 23: 353-363, 1967 4. Eliska O: Blood flow th...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 1994
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.17.1516